Under what circumstance is it acceptable to apply a deferral?

Applying a deferral is an important aspect of ensuring the safety and quality of the plasma donation process. A deferral can be implemented when a donor refuses a drug test, as this situation poses a significant risk. Drug testing is essential to maintain the integrity of the donated plasma and to protect both the donor and the recipients of the plasma products. Without a drug test, potential contamination or the presence of harmful substances cannot be assessed, thus requiring a deferral until the issue is resolved.

In contrast, while other circumstances such as having a cold or being under 18 might warrant careful consideration regarding eligibility, they do not inherently trigger a deferral in the same direct manner as refusal to undergo a drug test. Plasma being too cloudy is a separate concern that directly relates to the quality of the plasma rather than the eligibility of the donor. Hence, the refusal of a drug test stands out as a clear and valid reason for deferral in the context of safeguarding the plasma donation process.