When must a plasma unit be manually entered into quarantine?

A plasma unit must be manually entered into quarantine when the volume is changed below the minimum limit. This is important because maintaining a minimum volume ensures that the collected plasma meets the necessary quality and safety standards for testing and processing. If the volume is insufficient, it could pose risks not only to the efficacy of the plasma in therapeutic use but also to the overall safety of the donation. Quarantining such units allows for proper review and consideration before they can be released for use, ensuring that all collected plasma is safe and meets regulatory requirements.

Options surrounding first-time donors, deferral situations, and equipment failure provide important context in donation scenarios, but they don’t specifically address the need for quarantine based on volume limits. Those situations might entail other procedural steps or considerations but would not justify a manual quarantine based solely on volume discrepancies.