Which of the following may indicate inadequate blood/plasma flow during a procedure?

The indication of inadequate blood/plasma flow during a procedure is reflected in the observable color change in the plasma. When there is insufficient blood flow, the plasma may not appear as vibrant or clear as it should, and instead might take on a different hue, indicating that the collection process is not functioning optimally. This change can be attributed to the decreased oxygenation and overall fluid dynamics, making the plasma appear darker or more opaque.

Considering the other options, a strong pulse can suggest that blood is circulating effectively, while an elevation in blood pressure typically shows that there is sufficient or even excess flow. Cold extremities can sometimes be a sign of reduced blood perfusion to peripheral areas, but it's less directly indicative of the flow in the context of plasma collection compared to the specific changes in plasma color. Thus, the color change serves as a direct and observable indicator of the adequacy of plasma flow during the procedure.